Hypomelanosis of Ito - DermNet
What is hypomelanosis of Ito? Hypomelanosis of Ito is part of a rare genetic neurocutaneous syndrome. It is characterised by: Streaky, patchy, whorl-like, or linear hypopigmented macules occurring on any part of the body. Palms, scalp and soles of the feet are usually not affected.
Hypomelanosis of Ito - Symptoms, Causes, Treatment | NORD
Jan 17, 2017 · Hypomelanosis of Ito is a rare condition characterized by distinctive skin changes, in which areas of the body lack skin color (hypopigmentation). These skin changes may present as patches, streaks or spiral-shaped (whorled) areas.
Hypomelanosis of Ito | About the Disease | GARD - Genetic and …
Hypomelanosis of Ito, also called incontinentia pigmenti achromians, causes streaked, whirled, or mottled patches of light-colored skin. Other symptoms may include varying degrees of learning disability, seizures, increased body hair, scoliosis, and strabismus. The exact cause is not known.
Hypomelanosis of Ito Information | Mount Sinai - New York
Hypomelanosis of Ito (HMI) is a rare birth defect that causes light-colored patches of skin and may affect eyes, nerves, and bones. Learn about the possible causes, symptoms, diagnosis, treatment, and outlook of HMI from Mount Sinai Health Library.
Hypomelanosis of Ito: Practice Essentials, Pathophysiology, Etiology
Apr 14, 2023 · Hypomelanosis of Ito is a pigmentary mosaicism characterized by a clone of skin cells with decreased ability to produce pigment. The clinical pattern is characterized by...
Incontinentia Pigmenti - GeneReviews® - NCBI Bookshelf
Jun 8, 1999 · Hypomelanosis of Ito (OMIM 300337) is a phenotype related to chromosomal mosaicism. Another important differentiation is that in individuals with IP the hyper pigmented areas are abnormal, whereas in hypomelanosis of Ito hypo pigmentated areas are abnormal.
Hypomelanosis of Ito - MedLink Neurology
Jun 10, 1997 · Learn about the skin and systemic features of hypomelanosis of Ito, a sporadic neurocutaneous disorder with mosaic chromosomal abnormalities. The article covers historical note, terminology, pathogenesis, and neurologic manifestations.
Hypomelanosis of Ito - PubMed
Hypomelanosis of Ito, initially referred to as incontinentia pigmenti achromians, is a rare neurocutaneous disorder. Hypopigmented lesions following the lines of Blaschko are usually the presenting feature.
Hypomelanosis of Ito - SpringerLink
Hypomelanosis of Ito (HI) is a neurocutaneous disease characterized by linear nevoid hypopigmented lesions on the trunk and extremities, progressing along Blaschko’s lines, with systemic involvement such as the central nervous system, musculoskeletal system, and eyes.
Hypomelanosis of Ito - SpringerLink
Hypomelanosis of Ito (HI) is a relatively common disorder with a frequency of 1 in 8,000–10,000 patients in a general pediatric hospital and 1 in 1,000 patients in a pediatric neurology service (Küster and Konig 1999).